What is PB Serum HA?
PB Serum HA is a lyophilised (freeze-dried) enzyme-based treatment mixed with high-molecular-weight hyaluronic acid before injection. Each formula contains the same “base” concept—HA plus recombinant enzymes—but in different proportions to address different concerns:
- Lyase – breaks down sugar-based molecules that trap fluid; helps reduce puffiness and improve tissue drainage.
- Lipase – helps empty fat cells and smooth localised fat deposits without damaging surrounding structures.
- Collagenase – remodels disorganised collagen, softening scars and fibrotic, hardened areas.
Because of this flexible system, PB Serum HA can be customised as Low, Medium or High, depending on whether the priority is puffiness, fat, cellulite, scars or fibrotic nodules.
PB Serum Low / Medium / High at a Glance
PB Serum Low – Drain & Define
- Main focus: Lyase-dominant formula
- Primary target: Fluid retention, early fibrosis and mild volume build-up in soft tissues
Best suited for:
- Puffy or swollen areas (e.g. under-eye bags, malar bags)
- “Heavy” lower face or jowls with mild fullness
- Early fibrotic change where the skin feels thicker or less supple
Typical treatment goals:
- Under-eye and mid-face debulking with skin tightening
- Subtle lower-face reshaping and jowl contour refinement
- Softening of early fibrotic tissue and improving skin texture
PB Serum Medium – Sculpt Localised Fat
- Main focus: Lipase-dominant formula
- Primary target: Localised fat deposits and adipose-related cellulite
Best suited for:
- Double chin and jawline fullness
- Small, stubborn fat pockets – bra bulge, upper arms, tummy rolls, love handles
- Cellulite areas where fat and fibrotic bands coexist
Typical treatment goals:
- Non-surgical body contouring (abdomen, arms, thighs, flanks)
- Double-chin reduction with improved neck–jaw definition
- Cellulite smoothing by addressing both fat cells and fibrous bands
PB Serum High – Remodel Scars & Fibrosis
- Main focus: Collagenase-dominant formula
- Primary target: Disorganised collagen and fibrotic tissue (thickened, hardened areas)
Best suited for:
- Surgical, traumatic or acne scars (including hypertrophic / keloid-prone areas, depending on assessment)
- Fibrosis after procedures such as liposuction or trauma-related nodules
- Stretch marks and cellulite with strong fibrotic components
Typical treatment goals:
- Scar remodelling (surgical scars, acne scars, post-injury scars)
- Softening of nodules, adhesions and fibrotic plaques
- Improving the look and feel of stretch marks and hardened, dimpled tissue
What concerns can PB Serum help with?
Depending on whether Low, Medium or High is used—or a combination—PB Serum can be tailored for a wide range of face and body concerns:
Face & neck
- Under-eye bags and puffy lower eyelids
- Heavy jowls or lower-face fullness
- Double chin / submental fat
- Early skin laxity and poor definition of jawline
- Facial contour refinement
Scars & fibrosis
- Surgical and traumatic scars
- Acne scars (selected cases)
- Fibrosis after liposuction or other procedures
- Localised nodules and hardened areas
Body & cellulite
- Stubborn bulges (abdomen, flanks, arms, thighs, bra line)
- Cellulite with dimpled, uneven texture
- Stretch marks with underlying fibrotic change
Your AUREIGN AESTHETICS doctor will assess your skin, tissue quality and goals to decide which PB Serum strength—and which injection pattern—is most appropriate.
Facial Rejuvenation
HA Complications
Scars
Postsurgical Fibrosis
Skin health & appearance
Acne Scars
Hands Rejuvenation
Periocular Rejuvenation
Frequently Asked Questions
How is PB Serum HA different from regular fat-melting injections?
PB Serum HA is not a traditional chemical lipolysis product. Instead of relying on one aggressive ingredient, it uses recombinant enzymes—lyase, lipase and collagenase—combined with hyaluronic acid to selectively act on fluid, fat or fibrotic collagen. This allows the doctor to choose Low, Medium or High depending on whether the main problem is puffiness, fat pockets, scars or fibrosis, often with less swelling and downtime compared to older-style lipolytics.
What does a typical PB Serum treatment plan look like?
Most people start with a series of sessions rather than a single injection. A common protocol is:
- 3–5 sessions, spaced about 2–4 weeks apart, depending on the area and concern
- Small amounts injected via fine needle or cannula into targeted zones
- Maintenance top-ups may be advised once or twice a year for ongoing concerns such as cellulite or chronic scars
Your doctor will personalise the number of sessions based on how your tissue responds.
When will I see results?
Many people notice early changes—such as reduced puffiness, a lighter feel or softer tissue—within the first few weeks. Improvements in contour, texture and scar remodelling continue to evolve over several weeks to months as the enzymes trigger tissue regeneration and remodelling. Results and speed of change vary with the indication (for example, under-eye bags versus long-standing scars).
What is the downtime like?
PB Serum is considered a minimally invasive treatment. After the procedure you may experience:
- Redness, swelling or mild bruising at injection points
- Temporary tenderness or a feeling of “fullness” in the treated area
These usually settle over a few days. Most people are able to return to normal daily activities shortly after treatment, though your doctor may advise avoiding intense exercise, saunas or massages on the treated area for a short period.
Is PB Serum HA safe?
PB Serum uses recombinant enzymes, designed to closely mimic human enzymes with a low level of immunogenicity, and has been studied across multiple indications such as localised fat, cellulite and scar fibrosis. Serious complications are rare when treatment is performed by trained medical professionals using proper protocols, but all injectable procedures carry risks including bruising, swelling, temporary discomfort, infection or, very rarely, more serious events. A thorough consultation and medical history review are essential before treatment.
Who is not suitable for PB Serum treatment?
PB Serum is not recommended for individuals who are:
- Pregnant or breastfeeding
- Experiencing active skin infection or inflammation in the treatment area
- Known to have severe allergies to any component of the product
- Living with certain uncontrolled medical conditions, as assessed by the doctor
PB Serum is also not a weight-loss treatment; it is designed for targeted shaping, scars and tissue quality, not for overall reduction in body weight.
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Personalised AestheticsYour features, preferences and goals guide your treatment plan. Our focus is on helping you look and feel your best.
Personalised Aesthetic CareWe focus on individual needs and non-surgical aesthetic services to help you look and feel your best.
Tailored Solutions for You:
Our team focuses on finding the right treatment that aligns with your needs and expectations.
Individual AssessmentTreatment suitability, preparation, recovery and aftercare should be discussed before any procedure.
A Range of Treatment OptionsExplore facial rejuvenation, skin improvement, injectable aesthetics, energy-based treatments and body management.
Skin ImprovementOur focus includes skin texture, tone, hydration and the visible signs of ageing, with care tailored to individual concerns.
Please avoid self-diagnosing based on casual information found on the internet. Using products unsuitable for your specific skin condition could worsen the issue significantly.
Every treatment plan should reflect your individual skin concerns, medical history and expectations.
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